Brian Biggs was born in Arkansas in 1968, moved to Texas in 1979, fled to New York City in 1987 to attend Parsons School of Design, lived in Paris France for a few years, ran away to San Francisco in 1993, and since 1999 he has lived in Philadelphia. He works in an old garage and writes about himself in the third person.
He has worked as an art director and graphic designer, animator for interactivity and multimedia projects, teacher, writer, and illustrator. He has written and drawn comics and graphic novels, designed publications, and illustrated for many many magazines and newspapers. He illustrates children's books, such Jon Scieszka's Frank Einstein series; for magazines, newspapers, and advertising; posters, toys and puzzles. He also works with animation, music, and various other media.